Mayo Clinic in Arizona is pleased to announce our fifth symposium on tackling challenging sinus disease. World leaders in the fields of otolaryngology-rhinology, allergy-immunology and basic sciences will address the most challenging aspects of managing sinusitis and other rhinologic disorders. The program includes expert debates and brainstorming sessions using highly interactive formats. Our goal is to synthesize innovative management strategies based upon the latest evidence as well as the experience of global experts. A module-based approach to problematic subtypes of sinus disease. Expert presentations on latest research in pathophysiology and treatment, a live prosection, and hands-on nasal endoscopy training for medical providers will be offered.