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Apr 2016
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Patient-derived Xenografts of Hematological Malignancies: Model Systems for Drug Development and Tumor Biology Research

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Overview

Key learning points:

  • How hematological patient-derived xenograft (PDX) models are established
  • How more super immune deficient mouse models have advanced development of hematological PDX models
  • Why hematological PDX models are more translational than cell line-derived models
  • How hematological PDX models can be employed in drug discovery and development

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