The 2nd Annual Summit on Practical and Emerging Trends in Lymphoid Malignancies and Multiple Myeloma will focus on the clinical and practical changes that will occur over the next 2 to 5 years. The summit is formatted to better foster discussion and debate on the evolution of treatment approaches, featuring individual patient populations through case-based discussions. Compelling data on the effects of novel strategies, such as chimeric antigen receptor-expressing T cells, new targets, and next generation antibody therapy, have led to an explosion of new information and agents in development for patients with hematologic malignancies. How these new agents will be incorporated into clinical care will become an ever-increasing challenge forcommunity oncologists as they treat the individual patient. The Summit on Practical and Emerging Trends in Lymphoid Malignancies and Multiple Myeloma assembles translational researchers, clinical researchers, and key community oncologists to address and meet the challenges of this rapidly developing area of oncology.