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Apr 2016
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Development of Canine Exome Sequencing Methods to Identify Disease-causing Variants

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Overview

In this webinar, the development and performance of these designs will be discussed in-depth, as well as the effect of various choices made during the bait designing process. The unique breeding history of the dog that shaped the phenotypical diversity, also affects the identification of disease-causing mutations. While the advantage for GWAS was already demonstrated in 2007, we recently showed that this equally applies for direct sequencing approaches like WES.

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